首页> 外国专利> METHOD FOR DIFFERENTIAL DIAGNOSTICS BETWEEN OSTEOGENIC AND BONE MARROW SARCOMAS, GIANT-CELL TUMOR AND INFLAMMATORY DISEASES OF LONG TUBULAR BONES

METHOD FOR DIFFERENTIAL DIAGNOSTICS BETWEEN OSTEOGENIC AND BONE MARROW SARCOMAS, GIANT-CELL TUMOR AND INFLAMMATORY DISEASES OF LONG TUBULAR BONES

机译:长管骨成骨和骨肉瘤,巨细胞瘤和炎症性疾病的鉴别诊断方法

摘要

FIELD: medicine, orthopedics, differential diagnostics. SUBSTANCE: one should carry out a full-size roentgenography of affected limb's segment in two mutually perpendicular projections. Roentgenographic studying is supplemented with a purposeful ultrasound scanning to detect the most characteristic signs for every of these diseases. For osteogenic sarcoma it is characteristic to detect active tumor osteogenesis as a palisade of spicules developed as a result of tumor - analogs of modified haversian canals and osteons in combination with reactive, periosteal osteogenesis which develops short fragment of exfoliated and calcified periosteum - Codmen's "peak", intensive neonagiogenesis - characteristic morphological peculiarity of lytic and mixed form of this sarcoma is proved due to ultrasound angiography in the course of which one should visualize blood cavities and vessels of different diameter with curved pathway in central and peripheral departments of osteosarcoma, most of them are localized to be parallel to spicules. Young's sarcoma is of diffusion-heterogeneous structure with foci of reactive osteogenesis and develops exfoliated periosteosis, surface tumor departments have lower echogeneity; active tumor osteogenesis is not observed. Giant-cell tumor is of relatively homogeneous structure; one should determine incompletely lysed osseous trabecules in the thickness; tumor vascularization is intensive, however, vascular architectonics is less curved and chaotic than in sarcomas. In case of acute osteomyelitis in children it is necessary to visualize periosteal exfoliation, in grown-ups one should detect purulent liquid outwards against periosteum. At chronic osteomyelitis one should detect granulation tissue outwards against exfoliated periosteum. For all forms of development it is characteristic the presence of cylindrical defects in periosteum and cortical layer. The present method enables to obtain diagnostic information on the character and degree of pathological process. EFFECT: higher efficiency of differential diagnostics. 54 dwg
机译:领域:医学,骨科,鉴别诊断。实质:应该对患肢的两段相互垂直的投影进行全尺寸的X线照相。放射线学研究辅以有目的的超声扫描,以检测每种疾病的最特征性体征。对于成骨肉瘤,特征在于可以检测出由于肿瘤而形成的针状骨形成的活动性肿瘤成骨作用-修饰的哈弗斯管和骨质类似物与反应性骨膜成骨作用相结合,后者会形成剥落和钙化的骨膜短片段-Codmen'speak “,密集的新生血管形成-这种肉瘤的溶解和混合形式具有特征性的形态特征,这是由于超声血管造影的结果,在此过程中,应可视化骨肉瘤的中央和周围部分的血液腔和直径不同的血管以及弯曲的路径,它们被定位成与针状体平行。杨氏肉瘤具有弥漫性异质性结构,反应性成骨灶,并发展为剥脱性骨膜病,表面肿瘤部回声较低。没有观察到活跃的肿瘤成骨作用。巨细胞瘤具有相对均质的结构;应该确定厚度不完全溶解的骨小梁;肿瘤的血管形成是密集的,但是,与肉瘤相比,血管结构的弯曲和混乱程度较小。如果儿童患有急性骨髓炎,则必须可视化骨膜剥脱,在成年人中,应该检测出针对骨膜的脓性液体向外。在慢性骨髓炎中,应该从肉芽组织中向外检出脱落的骨膜。对于所有形式的发育,骨膜和皮质层均存在圆柱状缺陷。本方法能够获得关于病理过程的特征和程度的诊断信息。效果:更高的鉴别诊断效率。 54载重吨

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