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Use of the (1S,2R) enantiomer of milnacipran for the preparation of a drug

机译:米那普仑的(1S,2R)对映异构体在制备药物中的用途

摘要

A method for treating or preventing a disorder or a condition by double inhibition of serotonin (5-HT) and noradrenaline (NA) reuptake in a subject in need thereof, while limiting the risks of cardiovascular disturbances and/or organ and/or tissue toxicity, comprising the step of administering to said subject a mixture of enantiomers of milnacipran enriched in the (1S,2R) enantiomer of milnacipran and/or of at least one of its metabolites, as well as their pharmaceutically-acceptable salts.
机译:通过双重抑制5-羟色胺(5-HT)和去甲肾上腺素(NA)再摄取来治疗或预防疾病或病症的方法,同时限制心血管疾病和/或器官和/或组织毒性的风险包括向所述受试者给予富含米那普仑的(1S,2R)对映异构体和/或其至少一种代谢产物的米那普仑对映异构体混合物及其药学上可接受的盐的步骤。

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