HYBRID PROTEINS OF ACTIVE-SITE SERINE BETA-LACTAMASE

摘要

The present invention refers to a recombinant nucleotide sequence which codes upon expression for at least a part of a bifunctional hybrid active-site serine beta-­lactamase protein, wherein the beta-lactamase protein is bearing at least one heterologous sequence, wherein in that the hybrid protein is having two functions, the first function is associated with the beta-lactamase portion and the second function is associated with the heterologous sequence having a biological function which is different from the first function.