NEW METHOD FOR SYNTHESIS OF 5-(4-FLUOROPHENYL)-1-2-((2R, 4R)-4-HYDROXY-6-OXO-TETRAHYDROPYRAN-2-YL)-ETHYL-2-ISOPROPYL-4-PHENYL-1H-PYRROLE-3-CARBOXYLIC ACID PHENYLAMIDE

摘要

PPROBLEM TO BE SOLVED: To provide a new method for producing 5-(4-fluorophenyl)-1-[2-((2R, 4R)-4-hydroxy-6-oxo-tetrahydropyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide. PSOLUTION: The method for producing 5-(4-fluorophenyl)-1-[2-((2R, 4R)-4-hydroxy-6-oxo-tetrahydropyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide comprises reacting a compound represented by formula (7) with another compound in a solvent while removing water. PCOPYRIGHT: (C)2008,JPO&INPIT