Synthesis of (2R, 4R)-2-N-tert-Butyloxycarbonyl Amino-4,5-epoxido-valeric Acid Methyl Ester

摘要

The stereoselective synthesis of (2R, 4R)-2-N-tert-butyloxycarbonyl amino-4, 5-epoxido- valeric acid methyl ester 8, which is the key intermediate for the synthesis of (2S, 2R) -3-trans-nitrocyclopropyl-alanine, was first accomplished.