The stereoselective synthesis of (2R, 4R)-2-N-tert-butyloxycarbonyl amino-4, 5-epoxido- valeric acid methyl ester 8, which is the key intermediate for the synthesis of (2S, 2R) -3-trans-nitrocyclopropyl-alanine, was first accomplished.
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State Key Laboratory of Drug Research Shanghai Institute of Materia Medica Shanghai Institute for Biological Sciences Chinese Academy of Sciences Shanghai 200031;
