Variant of an immunointeractive molecule comprising a portion having specificity for cross-linked fibrin derivatives from an immunointeractive molecule from an animal or avian

摘要

Humanised forms of the mouse monoclonal antibody DD-3B6/22 are described. This antibody is specific for D-dimer, a degradation fragment of crosslinked fibrin polymers. The use of these antibodies to detect blood clots in vivo is also included.