首页> 外国专利> PROCEDURES AND COMPOSITIONS OF TREATMENT OF NEOVASCULARIZATION AND EYE NERVOUS INJURIES.

PROCEDURES AND COMPOSITIONS OF TREATMENT OF NEOVASCULARIZATION AND EYE NERVOUS INJURIES.

机译:新生血管化和眼神经损伤的治疗方法和组成。

摘要

Use of an alpha receptor agonist for the manufacture of a medicament for use in a procedure for the reduction or elimination of a decrease in neurosensory retinal function after laser treatment of choroidal neovascularization (CNV), while maintaining the effect Therapeutic vascular occlusion of said therapy, the procedure comprising the steps: a) administration to a mammal having a CNV of a therapeutically effective amount of said medicament containing an alpha receptor agonist, wherein said neuroprotector is selected from the group constituted by an alpha 2B selective agonist, alpha 2C selective agonist, clonidine and para-aminoclonidine; b) subjecting said mammal to laser irradiation of the CNV retinal locus; wherein the amount of neurosensory retinal function after stages a) and b) is greater than when said mammal is subjected to stage b) without stage a).
机译:α受体激动剂在制备药物中的用途,该药物用于在减轻或消除脉络膜新生血管形成(CNV)后神经感觉性视网膜功能降低的程序中使用,同时保持该疗法的治疗性血管阻塞,该方法包括以下步骤:a)向具有CNV的哺乳动物施用治疗有效量的包含α受体激动剂的所述药物,其中所述神经保护剂选自由α2B选择性激动剂,α2C选择性激动剂组成的组,可乐定和对氨基可乐定; b)对所述哺乳动物进行CNV视网膜基因座的激光照射;其中在阶段a)和b)之后的神经感觉视网膜功能的量大于当所述哺乳动物在没有阶段a)的情况下进行到阶段b)的情况。

著录项

  • 公开/公告号ES2322030T3

    专利类型

  • 公开/公告日2009-06-16

    原文格式PDF

  • 申请/专利权人 ALLERGAN INC.;

    申请/专利号ES20010990804T

  • 申请日2001-11-01

  • 分类号A61K41;C07D233/50;A61K31;A61K31/13;A61K31/4164;A61K31/4168;A61K31/495;A61K31/498;A61K31/502;A61K38/18;A61K38/57;A61K45;A61K45/06;A61P9/10;A61P9/14;A61P25/02;A61P27/02;A61P39;A61P41;A61P43;C07D403/12;

  • 国家 ES

  • 入库时间 2022-08-21 19:23:47

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