Use of cell-matrix for the preparation of epidermal equivalent able to be pigmented, is claimed. Independent claims are included for: (1) a process for preparing epidermal equivalent comprising culturing the cell-matrix on a dermal equivalent; (2) a epidermal equivalent comprising melanocytes with three or more dendrites or able to obtained by the process; (3) a skin equivalent comprising the epidermal equivalent; (4) a preparation of the skin equivalent containing functional pilous follicles comprising culturing the cell-matrix on a dermal equivalent, where the dermal equivalent comprises dermal papilla fibroblasts; (5) a kit for preparing the epidermal equivalent comprising the cell-matrix; (6) a compound evaluation kit comprising the epidermal or skin equivalent in a culture medium adapted to the skin equivalent; and (7) a process of product screening to identify new active agent comprising contacting the product to be tested with an epidermal equivalent and reading of the product effect on the epidermal equivalent. ACTIVITY : Antiallergic; Vulnerary; Antiulcer; Antipsoriatic; Dermatological. MECHANISM OF ACTION : None given. No biological data given.
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