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METHODS FOR INHIBITING RENAL NERVE ACTIVITY VIA AN INTRA-TO-EXTRAVASCULAR APPROACH

机译:通过血管内外方法抑制肾神经活动的方法

摘要

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues.
机译:提供了用于热诱导的肾神经调节的方法和设备。可以通过直接和/或间接施加热能来加热或冷却有助于肾功能的神经纤维,或者通过饲喂或灌注神经纤维的血管结构来实现热诱导的肾神经调节。在一些实施例中,可以经由一个或多个传感器来监视神经纤维,非目标组织或热能输送元件的参数,以控制热诱导的神经调节。在一些实施例中,可以提供保护元件以减少在非目标组织中引起的热损伤的程度。

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