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METHOD FOR PRODUCING OPTICALLY ACTIVE ISOPULEGOL AND OPTICALLY ACTIVE MENTHOL

机译:制备光学活性的异薄荷醇和光学活性的薄荷醇的方法

摘要

The purpose of the present invention is to provide a method for producing optically active isopulegol and optically active menthol which makes it possible to reduce production expenses and minimize environment-polluting waste. The present invention makes it possible to obtain optically active isopulegol with high yield and high selectivity by: obtaining optically active citronellal by asymmetrically isomerizing geraniol and/or nerol using a specific optically active ruthenium catalyst, and performing a selective ring-closing reaction of the optically active citronellal by using an aluminum catalyst obtained by mixing an aluminum alkyl compound and a specific hydroxy compound.
机译:发明内容本发明的目的是提供一种制备光学活性的异胡薄荷醇和光学活性的薄荷醇的方法,该方法可以减少生产费用并使对环境的污染废物最小化。本发明通过以下方法获得具有高收率和高选择性的旋光异胡薄荷醇:通过使用特定的旋光性钌催化剂使香叶醇和/或神经醇不对称异构化而获得旋光香茅醛,并对该旋光性进行选择性的闭环反应,这是可能的。通过使用将烷基铝化合物和特定的羟基化合物混合而得到的铝催化剂,得到活性的香茅醛。

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