METHOD FOR SCREENING HEPATOTOXICITY OF DRUG METABOLITE USING HUMAN LIVER MICROSOME

摘要

The present invention relates to a method for screening hepatotoxicity of a drug metabolite using human liver microsome (HLM), comprising steps of: 1) culturing hepatocarcinoma cells and treating hepatocarcinoma cells with a test material and HLM; 2) exchanging a medium and culturing the hepatocarcinoma cells; and confirming cytotoxicity in the hepatocarcinoma cells.;COPYRIGHT KIPO 2014;[Reference numerals] (AA) Cell survival rate (the rate compared to a control group)