Novel conjugates comprising TETRAGALNAC and methods for delivering oligonucleotides

摘要

Disclosed herein is 1) an oligonucleotide; 2) one or more tetraGalNAc ligands of formula (I), which may be the same or different; optionally 3) the same or different A modular composition comprising one or more linkers; and optionally 4) one or more targeting ligands, solubilizers, pharmacokinetic agents, lipids and / or masking agents.