Method and related system for determining the particle size distribution of a mixture of particles by performing Taylor dispersion

摘要

A method and related system for determining the particle size distribution of a mixture of particles by performing Taylor dispersion. This method is characterized by the step of injecting the sample into the capillary (100), the step of transferring the sample along the capillary under experimental conditions suitable for generating the Taylor dispersion phenomenon (110), and the Taylor dispersion. Generating a new signal (120), processing the signal to obtain an experimental Taylor signal 数 (130), and analyzing the experimental Taylor signal 【(200). The analysis step implements the experimental Taylor signal by implementing a constrained regularization algorithm that minimizes the cost function Hα that includes at least one constraint term associated with a constraint that must follow the amplitude distribution P (G (C)). An amplitude distribution P (G (c)) that makes it possible to decompose ## EQU3 ## into a sum of Gaussian functions is obtained, and the above minimization is a characteristic parameter of the Gaussian amplitude function P (G (c)). Performed for the interval of interest for the value of G (c).