A Function of Valproic acid in Suicide gene therapy

摘要

The present invention relates to a method for treating suicide gene therapy using a combination of valproic acid (VPA) and stem cells expressing suicide genes such as HSV-TK (herpes simplex virus type I thymidine kinase) And a function of raising the anticancer effect by enhancing the gap junction and enhancing the bystander effect by co-culturing the valproic acid-treated suicide gene expression-stem cells.