COMPLEX COMPOSITION COMPRISING METFORMIN, COENZYME Q10 AND STATIN AND USE FOR PREVENTING OR TREATING IMMUNE DISEASE

摘要

The present invention relates to a pharmaceutical use of metformin, coenzyme Q10 and statin used in preventing or treating an immune disease caused by disorder of immunization and, more specifically, to a pharmaceutical composition for preventing or treating an immune disease containing metformin, coenzyme Q10 and statin as active components. The treatement of immune disease by co-administration of metformin, coenzyme Q10 and statin according to the present invention controlls expression of TNF-a, IL-17, Th1 and/or Th17 which are inflammatory cytokine compared with a group independently treating metformin, coenzyme Q10 and statin. and effectively treating the immune diseases in a joint inflammation induced animal model, and inflammatory intestine disease-induced animal model.