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Q10 Complex composition comprising metformin coenzyme Q10 and statin and use for preventing or treating immune disease
Q10 Complex composition comprising metformin coenzyme Q10 and statin and use for preventing or treating immune disease
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机译:包含二甲双胍辅酶Q10和他汀类药物的Q10复合物组合物及其在预防或治疗免疫疾病中的用途
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摘要
The present invention relates to the pharmaceutical use of metformin, coenzyme Q10 and statins for preventing or treating immune diseases caused by abnormality of immune response. More specifically, the present invention relates to a pharmaceutical use of metformin, coenzyme Q10 and statin as an active ingredient And to a pharmaceutical composition for preventing or treating diseases. The treatment of immune diseases by the combined administration of metformin, coenzyme Q10 and statin according to the present invention is more effective than the treatment of inflammatory cytokines such as TNF-a, IL-17, Th1 and / or Th17 expression is remarkably suppressed, and these immune diseases can be effectively treated in an arthritis-induced animal model and an inflammatory intestinal disease-induced animal model.
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