TRAINING METHOD OF BIOLOGICAL NEURON NETWORK OF CULTURE GROWN ON MULTIPLE-ELECTRODE MATRIX

摘要

FIELD: biotechnologies.;SUBSTANCE: before a training process is started, preliminary stimulation is performed without any feedback, on the basis of which the most effective stimulating electrode is chosen, which will be used during training, and stimulation parameters are chosen; test stimulation is performed without any feedback on the chosen stimulating electrode, on the basis of which the most effective recording electrode is chosen to be used in the training process; a response criterion and a training criterion are chosen by adapting the above parameters and the criteria to physiological features of a biological neuron network in this very experiment; after the training process is finished, it is checked whether a training effect is preserved or not.;EFFECT: creation of a training protocol including an algorithm of determination of optimum parameters for an individual biological neuron network, which are used in the training protocol.;6 cl, 3 dwg