A composite structure having a high compressive strength, which is suitable for a flow channel, is produced by the number of components is reduced, while the excellent chemical resistance and the high stress tolerance, the a glass substrate and a resin substrate are to be maintained. A glass substrate surface with a hydrolyzable silicon compound is modified and the glass substrate is brought into contact with the resin substrate. Subsequently, the contact surface between the glass substrate and the resin substrate to a temperature of the glass transition temperature of up to the pyrolysis temperature of the resin substrate is heated, which gaps between the glass substrate and the resin substrate is eliminated, in order to bring into close contact with one another, and a chemical bond and / or armature effects between the glass substrate and the resin substrate by means of the hydrolyzable silicon compound causes. Consequently, the glass substrate and the resin substrate is firmly secured to one another.
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