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CONJUGATE OF GINSENOSIDE COMPOUND K AND GLYCOL CHITOSAN AND AN ANTI-TUMOR USE THEREOF
CONJUGATE OF GINSENOSIDE COMPOUND K AND GLYCOL CHITOSAN AND AN ANTI-TUMOR USE THEREOF
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机译:人参皂甙复合物K和乙二醇壳聚糖的结合及其抗肿瘤用途
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摘要
The present invention relates to a conjugate of ginsenoside compound K and glycol chitosan, a method for preparing the conjugate, and a pharmaceutical composition for treating cancer including the conjugate in a pharmaceutically acceptable carrier.;The conjugate of ginsenoside compound K and glycol chitosan of the present invention has cancer cell-specific anticancer activity because of increased water solubility relative to ginsenoside compound K, formation of nanosized self-aggregates in an aqueous solution, stability at neutral pH and release of the ginsenoside compound K at acidic pH due to pH sensitivity, thus having excellent effects as a composition for treating cancer.
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