A microsphere composition comprising rotigotine or a pharmaceutically acceptable salt thereof; at least one poly (lactide-co-glycolide) (PLGA); and at least one fatty acid, in which the rotigotine or its pharmaceutical salt thereof is 20-40%, the at least one PLGA is 57.5-72.5% and the at least one fatty acid is the 2.5-7.5% by weight with respect to the total weight of the composition.
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