首页> 外国专利> PHARMACEUTICAL COMPOSITION COMPRISING GINKGO BILOBA EXTRACT AND MATRIX OF SUSTAINED RELEASE HYDROPHILIC POLYMERS, AND ITS ORAL SUSTAINED RELEASE FORMULATION

PHARMACEUTICAL COMPOSITION COMPRISING GINKGO BILOBA EXTRACT AND MATRIX OF SUSTAINED RELEASE HYDROPHILIC POLYMERS, AND ITS ORAL SUSTAINED RELEASE FORMULATION

机译:含银杏叶提取物和缓释亲水聚合物基体的药物组合物及其口服缓释制剂

摘要

Provided in the present invention is a sustained-release oral formulation, comprising a leaf extract of Ginkgo biloba and a sustained-release matrix system. According to the present invention, the sustained-release oral formulation of the leaf extract of Ginkgo biloba is capable of regulating the absorption degree of an active ingredient in vivo by a controllable release speed. The formulation exhibits continuous absorption by the delayed release speed of the formulation while penetrating through a gastrointestinal tract, when being injected in the human body, and continuously exhibits platelet activating factor (PAF) inhibitory activities and antioxidant activities. Therefore, the formulation is expected to improve a patient compliance of dosage by once-per-day dosage, and to have high effects of treatment.
机译:本发明提供了一种缓释口服制剂,其包含银杏叶提取物和缓释基质系统。根据本发明,银杏叶提取物的缓释口服制剂能够通过可控的释放速度调节体内活性成分的吸收程度。当被注射到人体中时,该制剂通过制剂的延迟释放速度表现出连续的吸收,同时穿过胃肠道,并持续显示出血小板活化因子(PAF)抑制活性和抗氧化活性。因此,期望该制剂通过每天一次的剂量改善患者对剂量的依从性,并具有高的治疗效果。

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