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NOVEL LECTINS AND APPLICATIONS FOR THE DETECTION OF PATHOLOGICAL STATE MARKERS

机译:新型凝集素及其在病理状态标记检测中的应用

摘要

Multimenic lectins having a β-propeller architecture, formed from monomer modules of approximately 30 to 60 amino acids, in which the binding sites to the glycans are situated on a given side of the proteins and the O-terminus and N-terminus ends of the peptide chains on the other side of the proteins, characterized in that they are formed from 4 to 7 monomer modules, a single, or a plurality of, or all of the adjacent modules being linked to one another by the linkers linking the N-terminus end of one module to the C-terminus end of the adjacent module.
机译:由约30至60个氨基酸的单体模块形成的具有β-螺旋桨结构的多凝集素,其中与聚糖的结合位点位于蛋白质的给定侧,且其O端和N端端蛋白质另一侧的肽链,其特征在于它们由4至7个单体模块形成,单个或多个或所有或所有相邻模块通过连接N端的连接子相互连接一个模块的末端到相邻模块的C末端。

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