Diagnostic value of combined detection of myocardial markers, white blood cell count and platelet distribution width in patients with positive myocardial injury markers

摘要

Objective:To explore the diagnostic value of combined detection of myocardial markers, white blood cell (WBC) counts and platelet distribution width (PDW) in patients with positive myocardial injury markers.Methods: From January 2017 to January 2018, 100 patients with positive markers of myocardial injury in our hospital were selected as observation group, and 100 healthy people were selected as control group. Serum myocardial markers troponin I (cTnI), creatine kinase isoenzyme (CK-MB), myoglobin (MYO), WBC count, and PDW levels were measured at admission, and analyzed for individual indicators. And individual and combined detections of these indicators in early diagnosis of acute myocardial infarction (AMI) were analysed.Results: Serum cTnI, CK-MB, MYO, WBC count and PDW level were higher in the observation group than those in the control group, and the difference between the groups was statistically significant. Of the 100 patients with positive myocardial injury markers, 48 (48.00％) were diagnosed with AMI by final clinical diagnosis. Compared with the control group, the positive rate of serum index and the combined detection of five indicators in the observation group were significantly increased. The sensitivity and specificity of the five indicators combined detection and diagnosis of AMI were 95.83％ and 94.23％, respectively, which were higher than the individual detection of each index, and the difference was statistically significant.Conclusions: The combined detection of serum cTnI, CK-MB, MYO, WBC count and PDW is helpful for early diagnosis of AMI and can improve the sensitivity and specificity of diagnosis.