selective and reversible inhibitors of ubiquitin-specific proteases 7

摘要

patent for: "selective and reversible inhibitors of ubiquitin-specific proteases." The present invention relates to the quinazolin-4-one compounds of formula (I '), their preparation process and uses thereof. These compounds are useful as selective and reversible inhibitors of ubiniquitin-specific proteases, particularly usp7, for the treatment of, for example, cancer, neurodegenerative diseases, inflammatory disorders and viral infections.