new hydroquinoline-2-one derivatives as aldosterone synthetase inhibitors (cyp1 1 b2 or cyp1 1 b1)

摘要

1/1 summary "New hydroquinoline-2-one derivatives as aldosterone synthetase inhibitors (cyp1 1 b2 or cyp1 1 b1)" The invention provides novel compounds having the general formula (1) wherein r1, r2, r3, r4, r5 R6, R7, R9, R10, R11 and a are as defined herein, compositions including the compounds and methods of using the compounds. The compounds of formula (I) are useful as aldosterone synthetase inhibitors (cyp11b2 or cyp11b1) for the treatment of various disorders.