PolipÉptidos quimÉricos and methods to alter its location in the Membrane

摘要

Methods and compositions for reversibly Proteins locate in Outer cell surface including: Nucleic Acids encoding polypeptidesThe ligand binding domain (LBD) of nuclear Hormone Receptor.Adding the ligand polypeptide can be located on the extracellular side of the plasma membrane; extracting polypeptide ligand can be removed.Construction of nucleic acid with LBD can be incorporated into polypeptide Antigen binding domain.Polypeptide can be introduced into Mammalian Cell; Introducing the ligand Domain, that is located on the extracellular side of the Membrane; extracting Domain ligand, withdrew.Applications for controlling toxicity of T lymphocytes.