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Single chain intrabodies that alter huntingtin mutant degradation
Single chain intrabodies that alter huntingtin mutant degradation
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机译:改变亨廷顿蛋白突变体降解的单链抗体
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摘要
Compositions and methods of use are provided for intrabodies that bind and alter the effects of poly-glutamate protein aggregation in poly-glutamate associated diseases, such as in Huntington's disease. Intrabodies are provided that prevent poly-glutamate aggregation, gene dysregulation, and negative effects of Huntington's disease.
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