The present invention relates to a method for diagnosing diseases through oligomer analysis of abnormal aggregated proteins, comprising the steps of: preparing a body fluid sample comprising at least one of blood, plasma, serum, saliva, urine, tears and runny nose; diluting a body fluid sample Measuring and detecting the cohesive protein in the diluted body fluid sample using the biosensor and analyzing the signal change of the biosensor according to the dilution of the cohesive protein to generate a gradient according to concentration dilution from the measured value, And analyzing and diagnosing the oligomer ratio from the slope, wherein the impedance and protein concentration of the blood are measured using a biosensor and the slope of the concentration of the monomer and the oligomer is detected to detect normal or abnormal protein aggregation or disease And the like can be diagnosed more accurately.
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