3 Methods and kits for the PIK3CA mutant detection using PNA mediated Real-time PCR clamping

摘要

The present invention relates to a method for selectively detecting mutations by inhibiting amplification of wild type using a PNA (Peptide Nucleic Acid) probe that specifically binds to the wild type of PIK3CA gene exon 9 or 20, and a kit for use in the method will be.