process for evaluating rheological characteristics of an injectable gel, methods for comparing dermal fillers and determining a flexibility value for an injectable gel, and computer program product

摘要

The present invention provides a method for evaluating rheological characteristics of an injectable gel comprising measuring flexibility, wherein flexibility is assessed by measuring strain sweep crossing point deformation. As an example, the process may comprise subjecting an injectable gel to oscillating mechanical stresses to determine g? and g ?? As a function of the strain (¿) in an amplitude scan, determine the crossing point as the point at which g? and g ?? have the same value, determine the crass deformation at the crossing point, and determine the flexibility of the injectable gel as crass or proportional to the cross. The present invention further provides a method of comparing dermal fillers by measuring its flexibility and a method of evaluating dermal filler behavior in human skin by measuring flexibility according to the preceding claims.