AN OCTAHYDROTHIENOQUINOLINE DERIVATIVE, A PHARMACEUTICAL COMPOSITION COMPRISING THE DERIVATIVE, AND USE THEREOF AS A DOPAMINE D2 RECEPTOR AGONIST

摘要

The present invention provides compounds represented by the general formula(I): or pharmaceutical acceptable salts thereof, wherein R1 is cyano or thelike; R2 andR3 are hydrogen or the like; R4 is C1-6 alkyl or the like; R5 is C1-6 alkyl,halo-C1-6 alkyl,cycloalkyl, cycloalkyl-C1-6 alkyl, aralkyl or the like; R6 and R7 are eachhydrogen, C1-6alkyl, halo-C1..6 alkyl, cycloalkyl, C1-6 alkoxy-C1-6 alkyl, R12R13N-C1-6alkyl or the like,which exhibit potent dopamine D2 receptor stimulating activities. The presentinventionalso provides pharmaceutical compositions containing said compound, and usesthereof.(see formula I)