METHOD FOR CLASSIFYING MEDULLOBLASTOMA PATIENTS INTO MOLECULAR SUB-GROUPS

摘要

The present invention relates to use of the combination of the cytosine methylation profiles from the WNT-SHH panel and the G3-G4 panel as a marker for classifying medulloblastoma patients into the WNT, SHH, Group 3 and Group 4 sub-groups. The invention also relates to the method for classifying medulloblastoma patients into one of said molecular sub-groups based on the cytosine methylation analysis in the WNT-SHH and G3-G4 panels. Finally, the invention relates to the kit for carrying out the classification method of the invention.