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TRANSDERMAL SHORT PEPTIDE HAVING NUCLEAR POSITIONING CAPABILITY AND APPLICATIONS THEREOF
TRANSDERMAL SHORT PEPTIDE HAVING NUCLEAR POSITIONING CAPABILITY AND APPLICATIONS THEREOF
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机译:具有核定位能力的经皮短肽及其应用
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摘要
Provided is a transdermal short peptide having nuclear positioning capability, the amino acid sequence thereof being as represented by SEQ ID No. 1; also provided is a fusion protein having nuclear positioning capability, comprising a macromolecular protein, one end of the macromolecular protein being connected to the transdermal short peptide. Also disclosed are applications of the short peptide in preparing a medicament or a transdermal preparation for treating skin diseases. Further provided in the present invention is the medicament for treating skin diseases, comprising the transdermal short peptide and a pharmaceutically acceptable excipient.
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机译:提供一种具有核定位能力的透皮短肽,其氨基酸序列如SEQ ID No.1所示。还提供了一种具有核定位能力的融合蛋白,其包含大分子蛋白质,大分子蛋白质的一端连接至透皮短肽。还公开了短肽在制备用于治疗皮肤疾病的药物或透皮制剂中的应用。本发明还提供了用于治疗皮肤疾病的药物,其包含透皮短肽和药学上可接受的赋形剂。
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