SHORT PEPTIDE ATR001, MONOCLONAL ANTIBODY PREPARED BY SHORT PEPTIDE AND HAVING FUNCTION OF BIASED REGULATION OF AT1R, AND APPLICATION THEREOF

摘要

A short peptide ATR001, a monoclonal antibody that is prepared by a short peptide and that has a function of the biased regulation of AT1R, and an application thereof; the short peptide ATR001 has an amino acid sequence of AFHYESQ, a hybridoma cell CQ8-A2D9, and a storage number thereof is: CCTCC NO: C2017108. Monoclonal antibody technology is used to prepare a monoclonal antibody targeting AT1R, and the antibody may have a function of the biased regulation of AT1R, having a therapeutic effect in vascular remodeling diseases such as hypertension, atherosclerosis and aneurysms.