The systems described herein generally relate to spinal cord stimulation (SCS) therapy and more particularly to monitoring the SCS therapy and determining an adjustment to a position of a lead or electrodes delivering the SCS therapy to the patient. The systems deliver a SCS therapy to a portion of an array of electrodes of a lead, and analyze physiological signals measured by a set of sensors relative to each other. The set of sensors are positioned bilaterally on a patient. Further, the systems determine an adjustment in a position of the lead or the SCS therapy based on a relation between the physiological signals.
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