The disclosed apparatus, systems and methods relate to the use of spinal cord stimulation (SCS) in the treatment of conditions correlated to the sympathetic nervous system. Stimulating the spinal cord via SCS to decrease muscle sympathetic nerve activity (MSNA). The methods include providing acute spinal cord stimulation and selectively increasing blood flow to tissues that are physically associated with the stimulated nerves, which is used to normalize blood pressure in hypertensive or hypotensive patients. The methods establish that acute SCS rapidly increases femoral vascular conductance and reduces peroneal MSNA.
展开▼