首页> 外国专利> Composition comprising perillyl alcohol or as active ingredients for muscle strengthening development differentiation regeneration or inhibiting muscle atrophy

Composition comprising perillyl alcohol or as active ingredients for muscle strengthening development differentiation regeneration or inhibiting muscle atrophy

机译:包含紫苏醇或作为用于肌肉增强发育分化再生或抑制肌肉萎缩的活性成分的组合物

摘要

The present invention relates to a composition for preventing or treating muscular diseases or improving muscle function comprising perillyl alcohol or a pharmaceutically acceptable salt thereof as an active ingredient, The expression of the protein involved in protein synthesis and muscle mass increase can be increased and the expression of the enzyme involved in the muscle protein degradation can be suppressed from the mRNA level. Therefore, muscle fatigue in muscular disease caused by decreased muscle function, muscle wasting or muscle regeneration, The present invention relates to a method for preventing or treating a muscle disorder, which comprises administering an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof, It can be used to promote or improve muscle function.
机译:本发明涉及用于预防或治疗肌肉疾病或改善肌肉功能的组合物,其包含紫苏醇或其药学上可接受的盐作为活性成分,可以增加参与蛋白质合成和肌肉质量增加的蛋白质的表达,并且该表达从mRNA水平可以抑制参与肌肉蛋白质降解的酶的活性。因此,由肌肉功能降低,肌肉消瘦或肌肉再生引起的肌肉疾病中的肌肉疲劳。本发明涉及预防或治疗肌肉疾病的方法,该方法包括给予有效量的式(I)化合物或其药学上可接受的盐,可以用于促进或改善肌肉功能。

著录项

  • 公开/公告号KR101996130B1

    专利类型

  • 公开/公告日2019-07-03

    原文格式PDF

  • 申请/专利权人 연세대학교 산학협력단;

    申请/专利号KR20170090876

  • 发明设计人 박태선;

    申请日2017-07-18

  • 分类号A61K31/045;A23L33/10;A61K8/34;A61Q19;

  • 国家 KR

  • 入库时间 2022-08-21 11:48:16

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