CRS Fragmented cysteinyl-tRNA synthetase peptide and use thereof

摘要

The present invention relates to a fragmented CRS peptide and a use thereof, and more particularly, to a peptide comprising the amino acid sequence of SEQ ID NO: 2; A peptide comprising an amino acid sequence showing at least 80% homology with the peptide; A polynucleotide encoding the peptide; A vector containing the polynucleotide; Host cells transformed with the vector; And to their use as vaccine adjuvants. The peptide disclosed in the present invention is a CRS fragment first disclosed in the present specification and exhibits anticancer activity and immune function enhancing activity. In addition, the peptide, the polynucleotide encoding the same, the vector containing the polynucleotide, the host cell transformed with the vector, or the CRS full-length protein are excellent in anticancer activity and immune function enhancement activity, so that vaccine adjuvants, vaccine compositions and cancer It can be very usefully used in the development of therapeutic compositions.