An anti-inflamatory composition comprising solid-state-fermented Caryopteris incana extract as an active ingredient and preparation method thereof

摘要

The present invention relates to an anti-inflammatory composition and a method for preparing the same, and a composition for anti-inflammatory containing as an active ingredient a dogwood extract, which is fermented with lactic acid bacteria ( Lactobacillus plantarum ) and has an increased anti-inflammatory effect, and the present inventors have a layer fermented with lactic acid bacteria ( Lactobacillus plantarum ). By reducing the expression of lipopolysaccharide (LPS)-induced inflammatory mediators in Raw 264.7 cells, flower tree extract effectively suppressed the inflammatory response of cells, and it was confirmed that the cytotoxicity was lower than that of non-fermented dogwood extract. Therefore, by establishing the fermentation system according to the present invention, it is expected that the toxicity of dogwood trees can be reduced and the anti-inflammatory activity can be increased to secure excellent herbal resources with high productivity of pharmacologically active compounds, and solid fermented dogwood extract is a new anti-inflammatory agent. It can be usefully used as an excellent material for development and a health functional food composition for improving inflammation.