A specific binding protein capable of specifically binding to human oncostatin M (hOSM) and its uses.

摘要

"Specific binding protein capable of specifically binding to human oncostatin M (hOSM) and uses thereof" The present invention relates to specific binding proteins, such as antibodies which specifically bind to oncostatin M (OSM), including human OSM (hOSM) and modulate the interaction between oncostatin M and gp130 and / or the LIF receptor. The invention also relates to pharmaceutical compositions and their uses in the prevention and / or treatment of diseases associated with an abnormal level of oncostatin M and in particular inflammatory skin diseases and cancer. The invention also relates to diagnostic compositions and their uses in the detection of diseases associated with an abnormal level of oncostatin M and in particular inflammatory skin diseases and cancer.