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用于增加疗效的可与细胞结合的免疫佐剂

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摘要

本案提供了能够调节免疫反应的治疗套组。该治疗套组还可用于增强从细胞碎片释放的抗原的免疫原性。并提供了使用该治疗套组的方法。

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公开/公告号CN111727054A

专利类型发明专利
公开/公告日2020-09-29

原文格式PDF
申请/专利权人中央研究院;
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申请/专利号CN201980007309.4
发明设计人胡哲铭;莎柏妮;
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申请日2019-01-03
分类号A61K39/395(20060101);A61K47/68(20170101);A61K9/51(20060101);A61K31/404(20060101);A61K31/517(20060101);A61K31/7056(20060101);A61K31/538(20060101);A61K31/655(20060101);A61K31/69(20060101);A61K31/175(20060101);A61K31/4196(20060101);A61K31/565(20060101);A61K31/5377(20060101);A61K31/675(20060101);A61K31/365(20060101);A61K31/7068(20060101);A61P35/00(20060101);A61P9/00(20060101);A61P37/02(20060101);A61P31/00(20060101);
代理机构11127 北京三友知识产权代理有限公司;
代理人韩蕾;李辉
地址中国台湾台北市南港区研究院路二段128号
入库时间 2023-06-19 08:23:55

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1. 用于增加疗效的可与细胞结合的免疫佐剂 [P] . 中国专利： CN111727054A . 2020-09-29
2. 用于增加移植后造血干细胞的植入疗效的新型组合物 [P] . 中国专利： CN107548305A . 2018-01-05
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机译：免疫功能检测方法，癌症患者分类方法，癌症治疗效果预测方法，用于增加细胞内钙离子浓度的药剂，用于增加肿瘤组织中效应记忆（EM）和效应（EFF）的选择性功能的剂，以及监测疗效的方法癌症药
4. isolated human antibody, method of treating a condition caused by increased ngf expression or increased ngf sensitivity in a patient, pharmaceutical composition, method for detecting ngf in a biological sample, nucleic acid molecule, host cell, isolated cell line, ngf-specific binding agent, isolated human antibody or immunologically functional immunoglobulin fragment or antigen binder thereof, polynucleotide, expression vector, medicament for treating a painful disorder or condition associated with increased ngf expression or increased sensitivity to ngf, and, use of a pharmaceutically effective amount of antibody [P] . BRPI0412567A . 2006-09-19

机译：分离的人抗体，治疗患者中ngf表达增加或ngf敏感性增加引起的疾病的方法，药物组合物，生物样品中ngf的检测方法，核酸分子，宿主细胞，分离的细胞系，ngf特异性结合剂，分离的人抗体或其免疫功能性免疫球蛋白片段或其抗原结合剂，多核苷酸，表达载体，用于治疗与ngf表达增加或对ngf敏感性增加相关的疼痛性疾病或病症的药物，以及药物有效量的抗体的用途
5. Modified immunoglobulin, molecule, isolated nucleic acid, cell containing the same, recombinant non-human animal, pharmaceutical composition, vaccine composition, processes for identifying or measuring or detecting a cancer antigen, an antigen from an infectious disease agent, a ligand, and a receptor in a sample. to be tested, kits for detecting a cancer antigen, an infectious disease agent antigen, a cell receptor for an infectious disease agent, a ligand, and a cancer antigen, diagnostic processes or testing for the presence of or a predisposition for the development of a cancer by the increased presence of a cancer antigen, and for the presence of an infectious disease, treatment or prevention of a cancer by the presence of a cancer antigen, of an infectious disease typified by the presence of an antigen infectious disease agent, and a disease caused by an infectious disease agent that binds to a cell receptor, processes for modulating activity of a first member of a binding pair, [P] . BR9815289A . 2001-12-26

机译：修饰的免疫球蛋白，分子，分离的核酸，含有相同免疫球蛋白的细胞，重组非人类动物，药物组合物，疫苗组合物，鉴定或测量或检测癌症抗原的方法，来自传染病原体的抗原，配体和样品中的受体。要测试的试剂盒，用于检测癌症抗原，传染病原体抗原，传染病原体的细胞受体，配体和癌症抗原的试剂盒，诊断过程或测试是否存在或易感通过增加癌症抗原的存在而引起的癌症，以及对于传染病的存在，通过癌症抗原的存在来治疗或预防癌症，以抗原传染病剂的存在为代表的传染病，以及由与细胞受体结合的传染病因子引起的疾病，调节结合对第一个成员的活性的过程，