Polydimethylsiloxane: An effective immune adjuvant and slow-release cytokine medium for local cancer treatment

摘要

Background and AimSilicone oil or gel has well-defined chemotactic properties on monocytes and lymphocytes in vivo. It results in fibrotic reaction when spread into the human tissues either incidentally or purposely and can slowly release any physically-enclosed lyophilized compounds due to its viscosity. Our aim is to investigate whether polydimethylsiloxane could be considered as an effective medium in the local treatment of cancer.