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Automatic Generation of Integration and Preprocessing Ontologies for Biomedical Sources in a Distributed Scenario

机译:在分布式方案中自动生成生物医学资源的集成和预处理本体

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摘要

Access to a large number of remote data sources has boosted research in biomedicine, where different biological and clinical research projects are based on collaborative efforts among international organizations. In this scenario, the authors have developed various methods and tools in the area of database integration, using an ontological approach. This paper describes a method to automatically generate preprocessing structures (ontologies) within an ontology-based KDD model. These ontologies are obtained from the analysis of data sources, searching for: (i) valid numerical ranges (using clustering techniques), (ii) different scales, (iii) synonym transformations based on known dictionaries and (iv)typographical errors. To test the method, experiments were carried out with four biomedical databases―containing rheumatoid arthritis, gene expression patterns, biological processes and breast cancer patients― proving the performance of the approach. This method supports experts in data analysis processes, facilitating the detection of inconsistencies.
机译:对大量远程数据源的访问促进了生物医学研究,其中不同的生物学和临床研究项目基于国际组织之间的共同努力。在这种情况下,作者使用本体论方法开发了数据库集成领域中的各种方法和工具。本文介绍了一种在基于本体的KDD模型中自动生成预处理结构(本体)的方法。这些本体是通过对数据源的分析而获得的,搜索以下内容:(i)有效的数值范围(使用聚类技术),(ii)不同的比例尺,(iii)基于已知词典的同义词转换和(iv)印刷错误。为了测试该方法,对四个生物医学数据库(包括类风湿性关节炎,基因表达模式,生物学过程和乳腺癌患者)进行了实验,证明了该方法的有效性。该方法为数据分析过程中的专家提供支持,从而有助于发现不一致之处。

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