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Molecular Modeling Studies and Synthesis of Novel Methyl 2-(2-(4-Oxo-3-aryl-3,4-dihydroquinazolin-2-ylthio)acetamido)alkanoates with Potential Anti-cancer Activity as Inhibitors for Methionine Synthase

机译：分子建模研究和新型甲基二甲基（2-（4-氧代-3-芳基-3,4-二氢喹唑啉-2-基）乙酰氨基酰基）链烷醇酸酯的抗癌活性作为蛋氨酸合酶的抑制剂

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Ismail Mahmoud Elfekki; Walid Fathalla Mohamed Hassan; Hosam Eldin Abd Elhamed Elshihawy; Ibrahim Ahmed Ibrahim Ali; Elsayed Hussein Mostafa Eltamany;
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1. Molecular Modeling Studies and Synthesis of Novel Methyl 2-(2-(4-Oxo-3-aryl-3,4-dihydroquinazolin-2-ylthio)acetamido)alkanoates with Potential Anti-cancer Activity as Inhibitors for Methionine Synthase [J] . Ismail Mahmoud Elfekki, Walid Fathalla Mohamed Hassan, Hosam Eldin Abd Elhamed Elshihawy, Chemical and Pharmaceutical Bulletin . 2014,第7期

机译：具有潜在抗癌活性的蛋氨酸合酶抑制剂的新型2-（2-（4-（3-氧-3-芳基-3,4-二氢喹唑啉-2-基硫基）乙酰胺基）链烷酸甲酯的分子模型研究与合成
2. Molecular Modeling Studies and Synthesis of Novel Methyl 2-(2-(4-Oxo-3-aryl-3,4-dihydroquinazolin-2-ylthio)acetamido)alkanoates with Potential Anti-cancer Activity as Inhibitors for Methionine Synthase [J] . Chemical and Pharmaceutical Bulletin . 2014,第7期

机译：具有潜在抗癌活性的蛋氨酸合酶抑制剂的新型2-（2-（4-（氧代-3-芳基-3,4-二氢喹唑啉-2-基硫基）乙酰胺基）链烷酸甲酯的分子模型研究与合成
3. Molecular modeling studies and synthesis of novel quinoxaline derivatives with potential anti-cancer activity as inhibitors of methionine synthase [J] . Hosam Elshihawy, Mohamed Hammad Medicinal chemistry research: an international journal for rapid communications on design and mechanisms of action of biologically active agents . 2013,第7期

机译：潜在的抗癌活性作为蛋氨酸合酶抑制剂的新型喹喔啉衍生物的分子模型研究与合成
4. Synthesis and properties study of 1-(2-methyl-4-cyan-3-pyrrolyl)-2-{2-methyl-4-N-(2-(2-formyloxyethoxy)et-hyl)naphthalimide-3-thienyl}perfluorocyclopentene [C] . Xue LI, Jing-Jing LIU, Shou-Zhi PU International Workshop on Material Science and Environmental Engineering . 2016

机译：1-（2-甲基-4-青色-3-吡咯基）-2- {2-甲基-4- N-（2-（2-（2-（2-甲酰氧基乙氧基）ET-Hyl）萘酰亚胺 -3-的合成及性质研究 -3- Thienyl}全氟环戊烯
5. I:- Design, synthesis and study of nucleotide prodrugs. II:- Synthesis of 5-fluoro-6-[(2-aminoimidazol-1-yl)methyl]uracil (AIFU) and study of its mechanism of action as a thymidine phosphorylase inhibitor. III:- Design and synthesis of novel nucleotide analogs as alternative substrates for studying the mechanism of the thymidylate synthase-catalyzed reaction. [D] . Jain, Harsh Vardhan. 2010

机译：I：-核苷酸前药的设计，合成和研究。 II：5-氟-6-[（（2-氨基咪唑-1-基）甲基]尿嘧啶（AIFU）的合成及其作为胸苷磷酸化酶抑制剂的作用机理的研究。 III：-设计和合成新型核苷酸类似物作为研究底物胸苷酸合酶催化反应机理的替代底物。
6. Synthesis Antitumor Evaluation Molecular Modeling and Quantitative Structure–Activity Relationship (QSAR) of Novel 2-(4-Amino-6-N-substituted-135-triazin-2-yl)methylthio-4-chloro-5-methyl-N-(1H-benzodimidazol-2(3H)-ylidene)Benzenesulfonamides [O] . Łukasz Tomorowicz, Jarosław Sławiński, Beata Żołnowska, 2020

机译：新型2-（4-氨基-6-N-取代-135-三嗪-2-基）甲硫基 -4-氯的合成抗肿瘤评价分子建模和定量构效关系（QSAR） -5-甲基-N-（1H-苯并d咪唑-2（3H）-亚烷基）苯磺酰胺
7. Convenient syntheses of methyl 2-[2-(3-acetyl-4-methyl-2-oxo-1,2-dihydroquinolin-1-yl)acetamido] alkanoates and their O-regioisomers [O] . Ibrahim A. I. Ali, Walid Fathalla, S. M. El Rayes 2008

机译：方便合成2- [2-（3-乙酰基-4-甲基-2-氧代-1,2-二氢喹啉-1-基）乙酰氨基]链烷酸甲酯及其O-区域异构体

Molecular Modeling Studies and Synthesis of Novel Methyl 2-(2-(4-Oxo-3-aryl-3,4-dihydroquinazolin-2-ylthio)acetamido)alkanoates with Potential Anti-cancer Activity as Inhibitors for Methionine Synthase

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