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1-Aryl-3-(1-acylpiperidin-4-yl)urea Inhibitors of Human and Murine Soluble Epoxide Hydrolase: Structure−Activity Relationships, Pharmacokinetics, and Reduction of Inflammatory Pain

机译：1-芳基-3-（1-丙氨酸哌啶-4-基）人和鼠可溶性环氧化物水解酶的尿素抑制剂：结构活性关系，药代动力学和炎症疼痛的减少

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Tristan E. Rose; Christophe Morisseau; Jun-Yan Liu; Bora Inceoglu; Paul D. Jones; James R. Sanborn; Bruce D. Hammock;
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年度 2010
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1. 1-Aryl-3-(1-acylpiperidin-4-yl)urea inhibitors of human and murine soluble epoxide hydrolase: Structure-activity relationships, pharmacokinetics, and reduction of inflammatory pain [J] . Rose T.E., Morisseau C., Liu J.-Y., Journal of Medicinal Chemistry . 2010,第19期

机译：人和鼠类可溶性环氧水解酶的1-芳基-3-（1-酰基哌啶丁-4-基）脲抑制剂：结构活性关系，药代动力学和减轻炎症性疼痛
2. Pharmacophoric Modeling and Atom-Based 3D-QSAR of Novel 1-Aryl-3-(1-acylpiperidin-4-yl) Urea as Human Soluble Epoxide Hydrolase Inhibitors (sEHIs) [J] . Nirupam Das, Meenakshi Dhanawat, Akanksha Kulshrestha, Medicinal chemistry . 2011,第6期

机译：新型1-Aryl-3-（1-酰基哌啶丁-4-基）尿素作为人类可溶性环氧水解酶抑制剂（sEHIs）的药理建模和基于原子的3D-QSAR
3. Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models [J] . European journal of pharmaceutical sciences . 2013,第4a5期

机译：取代的苯基可改善小鼠模型中基于尿素的可溶性环氧化物水解酶抑制剂的药代动力学和抗炎作用
4. Structure-activity relationships and cellular activity of phosphopeptide-based inhibitors of Stat3 [C] . Zhiyong Ren, David R.Coleman, Pijus K.Mandal International Peptide Symposium;European Peptide Symposium . 2005

机译：STAT3基于磷酸肽的抑制剂的结构 - 活性关系和细胞活性
5. Exploring Structure-Activity Relationship Approaches on Epoxide Hydrolase Inhibitors [D] . Kitamura, Seiya. 2016

机译：环氧化物水解酶抑制剂的结构 - 活性关系方法
6. 1-Aryl-3-(1-acylpiperidin-4-yl)urea Inhibitors of Human and Murine Soluble Epoxide Hydrolase: Structure-Activity Relationships Pharmacokinetics and Reduction of Inflammatory Pain [O] . Tristan E. Rose, Christophe Morisseau, Jun-Yan Liu, -1

机译：1-芳基-3-（1- acylpiperidin -4-基）人和鼠可溶性环氧化物水解的尿素抑制剂：结构 - 活性关系药动学和炎性疼痛的减少
7. 1,3-Disubstituted Ureas Functionalized with Ether Groups are Potent Inhibitors of the Soluble Epoxide Hydrolase with Improved Pharmacokinetic Properties [O] . In-hae Kim, Hsing-ju Tsai, Kosuke Nishi, 2015

机译：用醚基官能化的1,3-二取代脲是可溶性环氧化物水解酶的有效抑制剂，具有改善的药代动力学特性

1-Aryl-3-(1-acylpiperidin-4-yl)urea Inhibitors of Human and Murine Soluble Epoxide Hydrolase: Structure−Activity Relationships, Pharmacokinetics, and Reduction of Inflammatory Pain

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