Final Report on the Reproductive Toxicity of Dibromoacetonitrile (CAS No. 3252-43-5) Administered in Diet to SD Rats

摘要

The purpose of this study was to assess the general reproductive and developmenttoxicities of dibromoacetonitrile (DBAN) in rats using the Short Term Reproductive and Developmental Toxicity Screening design. This approach is designed to identify the physiologic processes (development; female reproduction; male reproduction; various somatic organs/processes) that are the most sensitive to DBAN exposure. The data are being generated at the request of the U.S. E.P.A. N.H.E.E.R.L., which will use the data to identify water disinfectant by-products (and related compounds) that require further investigation.