The Preparation and Purification of Cellobiose-1-C14

摘要

Cellobiose, a sugar representative of the simplest repeating unit of cellulose, is of considerable value as a model compound and has frequently been used to study the degradation of carbohydrates in pulping processes. Radiochemically labeled cellobiose is useful in distinguishing the reactions of one end of the molecule from those of the other end and in mechanistic studies such as saccharinic acid formation and oxidation reactions in alkaline solution. The report describes the chemical synthesis of isotopically labeled cellobiose. This was synthesized by a series of chemical reactions using inert cellobiose as the starting compound, and was obtained in over 98.0 percent radiochemical purity by chromatographic purification of the acetylated crude material obtained in the synthesis. (Author)