Preparation and Brominating Properties of Some Halogenated N-Bromoacetamides.

摘要

The side-chain bromination of toluene at room temperature by N-bromosuccinimide may be accomplished readily by adding dibenzoyl peroxide to the reaction mixture. When equimolar amounts of certain metal chlorides (Lewis acids) are added, nuclear bromination of toluene readily can be achieved. Henue has shown that N-bromosuccinimide (NBS) brominates toluene exclusively in the side chain at 90 deg; whereas under the same conditions, perfluorination N-bromosuccinimide favored nuclear bromination of toluene.