The Reaction Pattern of Liver-Peroxysomes (=Microbodies) during Cell Injury.

摘要

The quantitative relation of dependency of microbodies, mitochondria, and cristae membrances confirms the participation of the microbodies in cellular metabolism. There is still lacking today the demonstration of 'peroxysomal diseases' but a number of idiopathic diseases must be considered from this viewpoint. These include hypercholesterinemia, hyperlipidemia, and hyperuremia (Hruban et al, 1972). It is possible that an insufficiency of the microbodies in the form of a defective microbody genesis or defective enzyme presence might lead to an intracellular accumulation of toxic metabolites which may have repercussions on other metabolic compartments.